hypervariable regions การใช้
- This region is known as the " hypervariable region ".
- There are two mitochondrial hypervariable regions used in human mitochondrial genealogical DNA testing.
- The rest of the V region between the hypervariable regions are called framework regions.
- The DNA match was based on one of seven small segments taken from the hypervariable regions.
- Humanised antibodies are produced by grafting murine hypervariable regions on amino acid domains into human antibodies.
- Still can't find out what / where a hypervariable region is in that context.
- For example, the QKRAA sequence is an amino acid motif in the third hypervariable region of HLA-DRB1 * 0401.
- Thus, this hypervariable region of VP2 is the obvious target for the molecular techniques applied for IBDV detection and strain variation studies.
- Since most sequence variation associated with immunoglobulins and T cell receptors are found in the CDRs, these regions are sometimes referred to as " hypervariable regions ".
- The combined sequence of variable light chain ( V L ) and variable heavy chain ( V H ) creates three hypervariable regions ( HV1, HV2, and HV3 ).
- Family Tree DNA's first mtDNA tests were for HVR1 ( hypervariable region 1 ) of the mtDNA . Eventually, they added a Plus test that tested for both HVR1 and HVR2.
- The largest ectodomain of ASCT1 and ASCT2, extracellular loop 2 ( ECL2 ), contains at its C-terminus a 21 residue hypervariable region between human, mouse, and hamster receptors.
- Version 3 of van Oven's Phylotree defines K1a1b1a by the highly polymorphic 114 in the second hypervariable region, 10978 and 12954 in the coding region, and 16234 in the first hypervariable region.
- Version 3 of van Oven's Phylotree defines K1a1b1a by the highly polymorphic 114 in the second hypervariable region, 10978 and 12954 in the coding region, and 16234 in the first hypervariable region.
- Among them, VP2 protein contains important neutralizing antigenic sites and elicits protective immune response and most of the amino acid ( AA ) changes between antigenically different IBDVs are clustered in the hypervariable region of VP2.
- A partial mitochondrial DNA sequence of Kw鋎ay D鋘 Ts 靚chi, containing information on the hypervariable region HVR2, bases 1 to 360, is available in the National Center for Biotechnology Information's genome sequencing database, GenBank, as accession number AF502945.